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Like all full-size pickups, Silverado comes in two- and four-wheel-drive versions, in 1500, 2500 and 3500 weight ranges, in short-and-long-bed bodies, with fendered (Fleetside) and nonfendered (Sportside) beds, two-, three, or four-door cabs in base, LS and LT trim levels. There are three V8 engines and one V6 to choose from with either a 5-speed manual or a 4-speed automatic.

Wheel flares are now available for 1500 series 4X4 models, a tonneau cover is available for all models, and the two smallest V8 engines have more power for 2000.